William,
No, I do not think that this verse means that Nathaniel was saved. He was certainly converted soon after, but here at this particular time in verse 47 there appears to be no definite indication that he had true saving faith in Christ. However, in verse 49, we do read that Nathaniel made a confession that Jesus was the "Son of God".
What Jesus was more than likely referring to with His comment about
guile (v. 47), was Isaac's remarks to Esau in regard to his brother Jacob who took the upper hand and became head of the family through
deceit/guile rather than implying that Nathaniel was saved. (Gen 27:18-35) And further in verse 51 there is an undeniable connection with Genesis 28 which also tells more of Jacob.
In His grace,
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