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And.... methinks it would be good to add that a woman only gets pregnant according to the providential working of God. Thus, even with perfect reproductive systems in both Adam and Eve, they could have gone childless for 100's of years, should that have been the Lord's will.
Yes, God is the one providentially in charge and He is also the One who gave the divine mandate to be fruitful and multiply. IMHO, a 100 year time is unthinkable. God gave the mandate, He provided the means, providing there would have been no fall, there would have been somewhat immediate conception. I also do not think that the original woman's reproductive cycle would have been 100 years. I do believe Gen 4 sheds allot of light on all this as Adam and Eve, even after the curse, had many children prior to Seth (at least Cain, Abel, and one woman). Additionally, there is a number of other births to Cain's side of the family prior to Seth being born (recorded in Gen 4). Thus, the 100 year lag time looks very doubtful to me, but again it is all speculation.

Reformed and Always Reforming,